Polymer–Surfactant System Based Amorphous Solid Dispersion: Precipitation Inhibition and Bioavailability Enhancement of Itraconazole

The rapid release of poorly water-soluble drugs from amorphous solid dispersion (ASD) is often associated with the generation of supersaturated solution, which provides a strong driving force for precipitation and results in reduced absorption. Precipitation inhibitors, such as polymers and surfacta...

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Detalles Bibliográficos
Autores principales: Feng, Disang, Peng, Tingting, Huang, Zhengwei, Singh, Vikramjeet, Shi, Yin, Wen, Ting, Lu, Ming, Quan, Guilan, Pan, Xin, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027051/
https://www.ncbi.nlm.nih.gov/pubmed/29695136
http://dx.doi.org/10.3390/pharmaceutics10020053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027051/
https://www.ncbi.nlm.nih.gov/pubmed/29695136
http://dx.doi.org/10.3390/pharmaceutics10020053

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