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Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors

Carbonic anhydrases (CAs) are a superfamily of metalloenzymes widespread in all life, classified into seven genetically different families (α–θ). These enzymes catalyse the reversible hydration of carbonic anhydride (CO(2)), generating bicarbonate (HCO(3)(−)) and protons (H(+)). Fifteen isoforms of...

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Detalles Bibliográficos
Autores principales: Chiaramonte, Niccolò, Romanelli, Maria Novella, Teodori, Elisabetta, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027070/
https://www.ncbi.nlm.nih.gov/pubmed/29795039
http://dx.doi.org/10.3390/metabo8020036