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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Ball-milling is usually used to prepare co-amorphous drug–amino acid (AA) mixtures. In this study, co-amorphous drug–AA mixtures were produced using spray-drying, a scalable industrially preferred preparation method. The influence of the solvent type and solvent composition was investigated. Mixture...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027151/ https://www.ncbi.nlm.nih.gov/pubmed/29649124 http://dx.doi.org/10.3390/pharmaceutics10020047 |