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Gadolinium Tagged Osteoprotegerin-Mimicking Peptide: A Novel Magnetic Resonance Imaging Biospecific Contrast Agent for the Inhibition of Osteoclastogenesis and Osteoclast Activity

The control of osteoblast/osteoclast cross-talk is crucial in the bone remodelling process and provides a target mechanism in the development of drugs for bone metabolic diseases. Osteoprotegerin is a key molecule in this biosignalling pathway as it inhibits osteoclastogenesis and osteoclast activat...

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Detalles Bibliográficos
Autores principales: Mbundi, Lubinda, Meikle, Steve T., Busquets, Rosa, Dowell, Nicholas G., Cercignani, Mara, Santin, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027169/
https://www.ncbi.nlm.nih.gov/pubmed/29865247
http://dx.doi.org/10.3390/nano8060399