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Gadolinium Tagged Osteoprotegerin-Mimicking Peptide: A Novel Magnetic Resonance Imaging Biospecific Contrast Agent for the Inhibition of Osteoclastogenesis and Osteoclast Activity
The control of osteoblast/osteoclast cross-talk is crucial in the bone remodelling process and provides a target mechanism in the development of drugs for bone metabolic diseases. Osteoprotegerin is a key molecule in this biosignalling pathway as it inhibits osteoclastogenesis and osteoclast activat...
Autores principales: | Mbundi, Lubinda, Meikle, Steve T., Busquets, Rosa, Dowell, Nicholas G., Cercignani, Mara, Santin, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027169/ https://www.ncbi.nlm.nih.gov/pubmed/29865247 http://dx.doi.org/10.3390/nano8060399 |
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