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Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics

The promise of nucleic acid based oligonucleotides as effective genetic therapies has been held back by their low bioavailability and poor cellular uptake to target tissues upon systemic administration. One such strategy to improve upon delivery is the use of short cell-penetrating peptides (CPPs) t...

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Detalles Bibliográficos
Autores principales: McClorey, Graham, Banerjee, Subhashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027240/
https://www.ncbi.nlm.nih.gov/pubmed/29734750
http://dx.doi.org/10.3390/biomedicines6020051