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Cell-Penetrating Peptides to Enhance Delivery of Oligonucleotide-Based Therapeutics
The promise of nucleic acid based oligonucleotides as effective genetic therapies has been held back by their low bioavailability and poor cellular uptake to target tissues upon systemic administration. One such strategy to improve upon delivery is the use of short cell-penetrating peptides (CPPs) t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027240/ https://www.ncbi.nlm.nih.gov/pubmed/29734750 http://dx.doi.org/10.3390/biomedicines6020051 |