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A 3D Microfluidic Model to Recapitulate Cancer Cell Migration and Invasion

We have developed a microfluidic-based culture chip to simulate cancer cell migration and invasion across the basement membrane. In this microfluidic chip, a 3D microenvironment is engineered to culture metastatic breast cancer cells (MX1) in a 3D tumor model. A chemo-attractant was incorporated to...

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Detalles Bibliográficos
Autores principales: Toh, Yi-Chin, Raja, Anju, Yu, Hanry, van Noort, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027283/
https://www.ncbi.nlm.nih.gov/pubmed/29642502
http://dx.doi.org/10.3390/bioengineering5020029