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Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure

Nearly half a century has passed since the demonstration that cannabis and its chief psychoactive component Δ(9)-THC lowers intraocular pressure (IOP). Elevated IOP remains the chief hallmark and therapeutic target for glaucoma, a condition that places millions at risk of blindness. It is likely tha...

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Detalles Bibliográficos
Autores principales: Miller, Sally, Kulkarni, Shashank, Ciesielski, Alex, Nikas, Spyros P., Mackie, Ken, Makriyannis, Alexandros, Straiker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027315/
https://www.ncbi.nlm.nih.gov/pubmed/29786643
http://dx.doi.org/10.3390/ph11020050