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NF-κB Activation in Lymphoid Malignancies: Genetics, Signaling, and Targeted Therapy

The NF-κB transcription factor family plays a crucial role in lymphocyte proliferation and survival. Consequently, aberrant NF-κB activation has been described in a variety of lymphoid malignancies, including diffuse large B-cell lymphoma, Hodgkin lymphoma, and adult T-cell leukemia. Several factors...

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Detalles Bibliográficos
Autores principales: Grondona, Paula, Bucher, Philip, Schulze-Osthoff, Klaus, Hailfinger, Stephan, Schmitt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027339/
https://www.ncbi.nlm.nih.gov/pubmed/29587428
http://dx.doi.org/10.3390/biomedicines6020038