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Comparing the Folds of Prions and Other Pathogenic Amyloids

Pathogenic amyloids are the main feature of several neurodegenerative disorders, such as Creutzfeldt–Jakob disease, Alzheimer’s disease, and Parkinson’s disease. High resolution structures of tau paired helical filaments (PHFs), amyloid-β(1-42) (Aβ(1-42)) fibrils, and α-synuclein fibrils were recent...

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Detalles Bibliográficos
Autores principales: Flores-Fernández, José Miguel, Rathod, Vineet, Wille, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027354/
https://www.ncbi.nlm.nih.gov/pubmed/29734684
http://dx.doi.org/10.3390/pathogens7020050