Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener

Benexate, a drug used clinically as a defensive type anti-ulcer agent, has poor solubility and a bitter taste. To improve its solubility, a crystal engineering approach was proposed with the formation of novel salts using an artificial sweetener as a salt co-former. This was also expected to address...

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Detalles Bibliográficos
Autores principales: Dwichandra Putra, Okky, Umeda, Daiki, Fujita, Eriko, Haraguchi, Tamami, Uchida, Takahiro, Yonemochi, Etsuo, Uekusa, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027452/
https://www.ncbi.nlm.nih.gov/pubmed/29861459
http://dx.doi.org/10.3390/pharmaceutics10020064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027452/
https://www.ncbi.nlm.nih.gov/pubmed/29861459
http://dx.doi.org/10.3390/pharmaceutics10020064

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