Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors

A series of benzamides incorporating 4-sulfamoyl moieties were obtained by reacting 4-sulfamoyl benzoic acid with primary and secondary amines and amino acids. These sulfonamides were investigated as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). The human (h) isoforms hCA II,...

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Detalles Bibliográficos
Autores principales: Abdoli, Morteza, Bozdag, Murat, Angeli, Andrea, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027465/
https://www.ncbi.nlm.nih.gov/pubmed/29857578
http://dx.doi.org/10.3390/metabo8020037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027465/
https://www.ncbi.nlm.nih.gov/pubmed/29857578
http://dx.doi.org/10.3390/metabo8020037

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