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Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges

Glioblastoma is the most common, malignant primary tumor of the central nervous system. The average prognosis for life expectancy after diagnosis, with the triad of surgery, chemotherapy, and radiation therapy, is less than 1.5 years. Chemotherapy treatment is mostly limited to temozolomide. In this...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha S., Awad, Ahmed J., Shabani, Saman, Doan, Ninh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027516/
https://www.ncbi.nlm.nih.gov/pubmed/29642535
http://dx.doi.org/10.3390/pharmaceutics10020045