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A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device

Three-dimensional (3D) models with cells arranged in clusters or spheroids have emerged as valuable tools to improve physiological relevance in drug screening. One of the challenges with cells cultured in 3D, especially for high-throughput applications, is to quickly and non-invasively assess the ce...

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Detalles Bibliográficos
Autores principales: Christoffersson, Jonas, Meier, Florian, Kempf, Henning, Schwanke, Kristin, Coffee, Michelle, Beilmann, Mario, Zweigerdt, Robert, Mandenius, Carl-Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027518/
https://www.ncbi.nlm.nih.gov/pubmed/29734702
http://dx.doi.org/10.3390/bioengineering5020036