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A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device
Three-dimensional (3D) models with cells arranged in clusters or spheroids have emerged as valuable tools to improve physiological relevance in drug screening. One of the challenges with cells cultured in 3D, especially for high-throughput applications, is to quickly and non-invasively assess the ce...
Autores principales: | Christoffersson, Jonas, Meier, Florian, Kempf, Henning, Schwanke, Kristin, Coffee, Michelle, Beilmann, Mario, Zweigerdt, Robert, Mandenius, Carl-Fredrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027518/ https://www.ncbi.nlm.nih.gov/pubmed/29734702 http://dx.doi.org/10.3390/bioengineering5020036 |
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