Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Application to a Pharmacokinetic Study in Rats

A simple, sensitive, and reliable reversed-phase, Ultra-High-Pressure Liquid Chromatography (UHPLC) coupled with a Diode Array Detector (DAD) method for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamide (NAPA), in rat plasma was developed and validate...

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Detalles Bibliográficos
Autores principales: Balla, Anusha, Cho, Kwan Hyung, Kim, Yu Chul, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027534/
https://www.ncbi.nlm.nih.gov/pubmed/29601501
http://dx.doi.org/10.3390/pharmaceutics10020041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027534/
https://www.ncbi.nlm.nih.gov/pubmed/29601501
http://dx.doi.org/10.3390/pharmaceutics10020041

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