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Regional chemotherapy by isolated limb perfusion prior to surgery compared with surgery and post-operative radiotherapy for primary, locally advanced extremity sarcoma: a comparison of matched cohorts

BACKGROUND: Induction chemotherapy by isolated limb perfusion (ILP) with melphalan and tumour necrosis factor-α is an effective strategy to facilitate limb-conserving surgery in locally advanced extremity sarcoma. In a comparison of cohorts matched for grade, size and surgical resectability, we comp...

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Detalles Bibliográficos
Autores principales: Jakob, Jens, Smith, Henry G., Wilkinson, Michelle J., Pencavel, Tim, Miah, Aisha B., Thomas, Joseph M., Tunn, Per-Ulf, Pilz, Lothar R., Strauss, Dirk C., Hohenberger, Peter, Hayes, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027577/
https://www.ncbi.nlm.nih.gov/pubmed/29988594
http://dx.doi.org/10.1186/s13569-018-0098-6