Cocrystal of Ibuprofen–Nicotinamide: Solid-State Characterization and In Vivo Analgesic Activity Evaluation

Ibuprofen is classified as a BCS class II drug which has low solubility and high permeability. We conducted the formation of the cocrystalline phase of ibuprofen with coformer nicotinamide to increase its solubility. The purpose of this study was to characterize the solid state of cocrystalline phas...

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Detalles Bibliográficos
Autores principales: Yuliandra, Yori, Zaini, Erizal, Syofyan, Syofyan, Pratiwi, Wenny, Putri, Lidiya Novita, Pratiwi, Yuti Sahra, Arifin, Helmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027666/
https://www.ncbi.nlm.nih.gov/pubmed/29867030
http://dx.doi.org/10.3390/scipharm86020023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027666/
https://www.ncbi.nlm.nih.gov/pubmed/29867030
http://dx.doi.org/10.3390/scipharm86020023

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