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Betulin-3,28-diphosphate as a Component of Combination Cytostatic Drugs for the Treatment of Ehrlich Ascites Carcinoma In Vitro and In Vivo Experiments

The activity of betulin-3,28-diphosphate (BDP) in combination with the cytostatics such as 5-fluorouracil (5-FU) and hydrazine sulfate (HS) was demonstrated by using the transplanted Ehrlich ascites carcinoma (EAC) in mice. The dose-dependent effect of combination drugs BDP + HS and BDP + 5-FU was r...

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Detalles Bibliográficos
Autores principales: Vorobyova, Olga, Deryabina, Olga, Malygina, Darina, Plotnikova, Nadezhda, Solovyeva, Anna, Belyaeva, Kseniya, Melnikova, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027669/
https://www.ncbi.nlm.nih.gov/pubmed/29690651
http://dx.doi.org/10.3390/scipharm86020017