Inhibition of integrin α(V)β(6) changes fibril thickness of stromal collagen in experimental carcinomas

BACKGROUND: Chemotherapeutic efficacy can be improved by targeting the structure and function of the extracellular matrix (ECM) in the carcinomal stroma. This can be accomplished by e.g. inhibiting TGF-β1 and -β3 or treating with Imatinib, which results in scarcer collagen fibril structure in xenogr...

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Detalles Bibliográficos
Autores principales: Olof Olsson, P., Gustafsson, Renata, Salnikov, Alexei V., Göthe, Maria, Zeller, Kathrin S., Friman, Tomas, Baldetorp, Bo, Koopman, Louise A., Weinreb, Paul H., Violette, Shelia M., Kalamajski, Sebastian, Heldin, Nils-Erik, Rubin, Kristofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027735/
https://www.ncbi.nlm.nih.gov/pubmed/29966518
http://dx.doi.org/10.1186/s12964-018-0249-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027735/
https://www.ncbi.nlm.nih.gov/pubmed/29966518
http://dx.doi.org/10.1186/s12964-018-0249-7

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