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Phosphorylation of different tau sites during progression of Alzheimer’s disease

Alzheimer’s disease is characterized by accumulation of amyloid plaques and tau aggregates in several cortical brain regions. Tau phosphorylation causes formation of neurofibrillary tangles and neuropil threads. Phosphorylation at tau Ser202/Thr205 is well characterized since labeling of this site i...

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Detalles Bibliográficos
Autores principales: Neddens, Joerg, Temmel, Magdalena, Flunkert, Stefanie, Kerschbaumer, Bianca, Hoeller, Christina, Loeffler, Tina, Niederkofler, Vera, Daum, Guenther, Attems, Johannes, Hutter-Paier, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027763/
https://www.ncbi.nlm.nih.gov/pubmed/29958544
http://dx.doi.org/10.1186/s40478-018-0557-6