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Expression of Fibroblast Growth Factor 21 and β-Klotho Regulates Hepatic Fibrosis through the Nuclear Factor-κB and c-Jun N-Terminal Kinase Pathways

BACKGROUND/AIMS: Fibroblast growth factor (FGF) 21 is associated with hepatic inflammation and fibrosis. However, little is known regarding the effects of inflammation and fibrosis on the β-Klotho and FGF21 pathway in the liver. METHODS: Enrolled patients had biopsy-confirmed viral or alcoholic hepa...

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Detalles Bibliográficos
Autores principales: Lee, Kyong Joo, Jang, Yoon Ok, Cha, Seung-Kuy, Kim, Moon Young, Park, Kyu-Sang, Eom, Young Woo, Baik, Soon Koo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027831/
https://www.ncbi.nlm.nih.gov/pubmed/29699061
http://dx.doi.org/10.5009/gnl17443