Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood–brain barrier

BACKGROUND: Dapoxetine (DPX) is the drug of choice for the specific treatment of premature ejaculation. DPX is characterized by relatively low bioavailability (42%) and short half-life (1.5 h). The aim of this study was to improve DPX bioavailability and delivery across the blood–brain barrier (BBB)...

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Detalles Bibliográficos
Autores principales: Abourehab, Mohammed AS, Ahmed, Osama AA, Balata, Gehan F, Almalki, Waleed H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027843/
https://www.ncbi.nlm.nih.gov/pubmed/29983562
http://dx.doi.org/10.2147/IJN.S168148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027843/
https://www.ncbi.nlm.nih.gov/pubmed/29983562
http://dx.doi.org/10.2147/IJN.S168148

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