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A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

The main pathological hallmarks in Alzheimer’s disease (AD) are the presence of extracellular amyloid plaques, primarily consisting of amyloid-β (Aβ) peptide, and the accumulation of paired helical filaments of hyperphosphorylated tau protein (PHF(-Tau)) within neurons. Since CA1 is one of the most...

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Detalles Bibliográficos
Autores principales: Furcila, Diana, DeFelipe, Javier, Alonso-Nanclares, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027945/
https://www.ncbi.nlm.nih.gov/pubmed/29914033
http://dx.doi.org/10.3233/JAD-180173