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In vivo expansion of functionally integrated GABAergic interneurons by targeted increase in neural progenitors

A central hypothesis for brain evolution is that it might occur via expansion of progenitor cells and subsequent lineage‐dependent formation of neural circuits. Here, we report in vivo amplification and functional integration of lineage‐specific circuitry in Drosophila. Levels of the cell fate deter...

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Detalles Bibliográficos
Autores principales: Shaw, Rachel E, Kottler, Benjamin, Ludlow, Zoe N, Buhl, Edgar, Kim, Dongwook, Morais da Silva, Sara, Miedzik, Alina, Coum, Antoine, Hodge, James JL, Hirth, Frank, Sousa‐Nunes, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028031/
https://www.ncbi.nlm.nih.gov/pubmed/29728368
http://dx.doi.org/10.15252/embj.201798163