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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release

Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4(+) T cells as part of the immune system’s surveillance of pathogens and malignancy. In the absence of peptide, MHC-II equilibrates between peptide-receptive and peptide-averse conformation...

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Detalles Bibliográficos
Autores principales: Negroni, Maria Pia, Stern, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028098/
https://www.ncbi.nlm.nih.gov/pubmed/29965980
http://dx.doi.org/10.1371/journal.pone.0199704