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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release
Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4(+) T cells as part of the immune system’s surveillance of pathogens and malignancy. In the absence of peptide, MHC-II equilibrates between peptide-receptive and peptide-averse conformation...
Autores principales: | Negroni, Maria Pia, Stern, Lawrence J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028098/ https://www.ncbi.nlm.nih.gov/pubmed/29965980 http://dx.doi.org/10.1371/journal.pone.0199704 |
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