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Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains

Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism by which chromatin regulators contribute to ASD risk remains poorly understood....

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Detalles Bibliográficos
Autores principales: Zhao, Ying-Tao, Kwon, Deborah Y., Johnson, Brian S., Fasolino, Maria, Lamonica, Janine M., Kim, Yoon Jung, Zhao, Boxuan Simen, He, Chuan, Vahedi, Golnaz, Kim, Tae Hoon, Zhou, Zhaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028126/
https://www.ncbi.nlm.nih.gov/pubmed/29848492
http://dx.doi.org/10.1101/gr.233775.117