Long-read sequencing of nascent RNA reveals coupling among RNA processing events

Pre-mRNA splicing is accomplished by the spliceosome, a megadalton complex that assembles de novo on each intron. Because spliceosome assembly and catalysis occur cotranscriptionally, we hypothesized that introns are removed in the order of their transcription in genomes dominated by constitutive sp...

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Detalles Bibliográficos
Autores principales: Herzel, Lydia, Straube, Korinna, Neugebauer, Karla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028129/
https://www.ncbi.nlm.nih.gov/pubmed/29903723
http://dx.doi.org/10.1101/gr.232025.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028129/
https://www.ncbi.nlm.nih.gov/pubmed/29903723
http://dx.doi.org/10.1101/gr.232025.117

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