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Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety

BACKGROUND: We have synthesized a sustained-release lidocaine sheet (SRLS) using biodegradable polymers and previously demonstrated its safety and long-term analgesic effect in the normal mucous membrane of healthy human volunteers. OBJECTIVES: The aim of this clinical study was to evaluate the effi...

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Detalles Bibliográficos
Autores principales: Suzuki, Toshiyuki, Kosugi, Kensuke, Suto, Takashi, Tobe, Masaru, Tabata, Yasuhiko, Yokoo, Satoshi, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028143/
https://www.ncbi.nlm.nih.gov/pubmed/29966016
http://dx.doi.org/10.1371/journal.pone.0200059