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Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety
BACKGROUND: We have synthesized a sustained-release lidocaine sheet (SRLS) using biodegradable polymers and previously demonstrated its safety and long-term analgesic effect in the normal mucous membrane of healthy human volunteers. OBJECTIVES: The aim of this clinical study was to evaluate the effi...
Autores principales: | Suzuki, Toshiyuki, Kosugi, Kensuke, Suto, Takashi, Tobe, Masaru, Tabata, Yasuhiko, Yokoo, Satoshi, Saito, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028143/ https://www.ncbi.nlm.nih.gov/pubmed/29966016 http://dx.doi.org/10.1371/journal.pone.0200059 |
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