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Inferring the Probability of the Derived vs. the Ancestral Allelic State at a Polymorphic Site
It is known that the allele ancestral to the variation at a polymorphic site cannot be assigned with certainty, and that the most frequently used method to assign the ancestral state—maximum parsimony—is prone to misinference. Estimates of counts of sites that have a certain number of copies of the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028244/ https://www.ncbi.nlm.nih.gov/pubmed/29769282 http://dx.doi.org/10.1534/genetics.118.301120 |