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Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory

Preterm infants often require prolonged oxygen supplementation and are at high risk of neurodevelopmental impairment. We recently reported that adult mice exposed to neonatal hyperoxia (postnatal day [P] 2 to 14) had spatial navigation memory deficits associated with hippocampal shrinkage. The mecha...

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Detalles Bibliográficos
Autores principales: Ramani, Manimaran, Kumar, Ranjit, Halloran, Brian, Lal, Charitharth Vivek, Ambalavanan, Namasivayam, McMahon, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028393/
https://www.ncbi.nlm.nih.gov/pubmed/29967535
http://dx.doi.org/10.1038/s41598-018-28220-4