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Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory
Preterm infants often require prolonged oxygen supplementation and are at high risk of neurodevelopmental impairment. We recently reported that adult mice exposed to neonatal hyperoxia (postnatal day [P] 2 to 14) had spatial navigation memory deficits associated with hippocampal shrinkage. The mecha...
Autores principales: | Ramani, Manimaran, Kumar, Ranjit, Halloran, Brian, Lal, Charitharth Vivek, Ambalavanan, Namasivayam, McMahon, Lori L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028393/ https://www.ncbi.nlm.nih.gov/pubmed/29967535 http://dx.doi.org/10.1038/s41598-018-28220-4 |
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