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Early alteration of epigenetic-related transcription in Huntington’s disease mouse models

Transcriptional dysregulation in Huntington’s disease (HD) affects the expression of genes involved in survival and neuronal functions throughout the progression of the pathology. In recent years, extensive research has focused on epigenetic and chromatin-modifying factors as a causative explanation...

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Detalles Bibliográficos
Autores principales: Hervás-Corpión, Irati, Guiretti, Deisy, Alcaraz-Iborra, Manuel, Olivares, Román, Campos-Caro, Antonio, Barco, Ángel, Valor, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028428/
https://www.ncbi.nlm.nih.gov/pubmed/29967375
http://dx.doi.org/10.1038/s41598-018-28185-4