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Death-associated protein kinase 1 mediates interleukin-1β production through regulating inlfammasome activation in Bv2 microglial cells and mice

Interleukin-1β (IL-1β) plays a crucial role in mediating inflammation and innate immunity response in the central nervous system. Death-associated protein kinase 1 (DAPK1) was shown to be involved in several cellular processes. Here, we investigated the effects of DAPK1 on IL-1β production in microg...

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Detalles Bibliográficos
Autores principales: Song, Limin, Pei, Lei, Hu, Lisha, Pan, Shangwen, Xiong, Wei, Liu, Min, Wu, Yan, Shang, You, Yao, Shanglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028446/
https://www.ncbi.nlm.nih.gov/pubmed/29967321
http://dx.doi.org/10.1038/s41598-018-27842-y