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Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon

Membrane proteins in bacteria are cotranslationally inserted into the plasma membrane through the SecYEG translocon. Ribosomes exposing the signal-anchor sequence (SAS) of a membrane protein are targeted to the translocon by the signal recognition particle (SRP) pathway. SRP scans translating riboso...

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Detalles Bibliográficos
Autores principales: Draycheva, Albena, Lee, Sejeong, Wintermeyer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028451/
https://www.ncbi.nlm.nih.gov/pubmed/29967439
http://dx.doi.org/10.1038/s41598-018-28262-8