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Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon
Membrane proteins in bacteria are cotranslationally inserted into the plasma membrane through the SecYEG translocon. Ribosomes exposing the signal-anchor sequence (SAS) of a membrane protein are targeted to the translocon by the signal recognition particle (SRP) pathway. SRP scans translating riboso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028451/ https://www.ncbi.nlm.nih.gov/pubmed/29967439 http://dx.doi.org/10.1038/s41598-018-28262-8 |