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BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin

The virulence factor pyocyanin and the intracellular second messenger cyclic diguanylate monophosphate (c-di-GMP) play key roles in regulating biofilm formation and multi-drug efflux pump expression in Pseudomonas aeruginosa. However, the crosstalk between these two signaling pathways remains unclea...

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Detalles Bibliográficos
Autores principales: Wang, Feng, He, Qing, Yin, Jia, Xu, Sujuan, Hu, Wei, Gu, Lichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028453/
https://www.ncbi.nlm.nih.gov/pubmed/29967320
http://dx.doi.org/10.1038/s41467-018-05004-y