Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair

Damaged DNA shows increased mobility, which can promote interactions with repair-conducive nuclear pore complexes (NPCs). This apparently random mobility is paradoxically abrogated upon disruption of microtubules or kinesins, factors that typically cooperate to mediate the directional movement of ma...

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Detalles Bibliográficos
Autores principales: Oshidari, Roxanne, Strecker, Jonathan, Chung, Daniel K. C., Abraham, Karan J., Chan, Janet N. Y., Damaren, Christopher J., Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028458/
https://www.ncbi.nlm.nih.gov/pubmed/29967403
http://dx.doi.org/10.1038/s41467-018-05009-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028458/
https://www.ncbi.nlm.nih.gov/pubmed/29967403
http://dx.doi.org/10.1038/s41467-018-05009-7

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