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Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
Damaged DNA shows increased mobility, which can promote interactions with repair-conducive nuclear pore complexes (NPCs). This apparently random mobility is paradoxically abrogated upon disruption of microtubules or kinesins, factors that typically cooperate to mediate the directional movement of ma...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028458/ https://www.ncbi.nlm.nih.gov/pubmed/29967403 http://dx.doi.org/10.1038/s41467-018-05009-7 |