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Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway

PURPOSE: Transient receptor potential melastatin member 7 (TRPM7), an ion channel and serine/threonine protein kinase, has been linked with distinct human malignancies. However, the role of TRPM7 in renal cell carcinoma (RCC) has not been investigated. The aim of this study is to determine whether T...

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Detalles Bibliográficos
Autores principales: Ha, Yun-Sok, Kim, Yeon-Yong, Yu, Na Hee, Chun, So Young, Choi, Seock Hwan, Lee, Jun Nyung, Kim, Bum Soo, Yoo, Eun Sang, Kwon, Tae Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028469/
https://www.ncbi.nlm.nih.gov/pubmed/29984342
http://dx.doi.org/10.4111/icu.2018.59.4.263