Tetrodotoxin-sensitive Na(v)s contribute to early and delayed afterdepolarizations in long QT arrhythmia models

Recent evidence suggests that neuronal Na(+) channels (nNa(v)s) contribute to catecholamine-promoted delayed afterdepolarizations (DADs) and catecholaminergic polymorphic ventricular tachycardia (CPVT). The newly identified overlap between CPVT and long QT (LQT) phenotypes has stoked interest in the...

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Detalles Bibliográficos
Autores principales: Koleske, Megan, Bonilla, Ingrid, Thomas, Justin, Zaman, Naveed, Baine, Stephen, Knollmann, Bjorn C., Veeraraghavan, Rengasayee, Györke, Sándor, Radwański, Przemysław B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028491/
https://www.ncbi.nlm.nih.gov/pubmed/29793933
http://dx.doi.org/10.1085/jgp.201711909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028491/
https://www.ncbi.nlm.nih.gov/pubmed/29793933
http://dx.doi.org/10.1085/jgp.201711909

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