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Tetrodotoxin-sensitive Na(v)s contribute to early and delayed afterdepolarizations in long QT arrhythmia models
Recent evidence suggests that neuronal Na(+) channels (nNa(v)s) contribute to catecholamine-promoted delayed afterdepolarizations (DADs) and catecholaminergic polymorphic ventricular tachycardia (CPVT). The newly identified overlap between CPVT and long QT (LQT) phenotypes has stoked interest in the...
Autores principales: | Koleske, Megan, Bonilla, Ingrid, Thomas, Justin, Zaman, Naveed, Baine, Stephen, Knollmann, Bjorn C., Veeraraghavan, Rengasayee, Györke, Sándor, Radwański, Przemysław B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028491/ https://www.ncbi.nlm.nih.gov/pubmed/29793933 http://dx.doi.org/10.1085/jgp.201711909 |
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