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Molecular determination of claudin-15 organization and channel selectivity

Tight junctions are macromolecular structures that traverse the space between adjacent cells in epithelia and endothelia. Members of the claudin family are known to determine tight junction permeability in a charge- and size-selective manner. Here, we use molecular dynamics simulations to build and...

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Detalles Bibliográficos
Autores principales: Samanta, Priyanka, Wang, Yitang, Fuladi, Shadi, Zou, Jinjing, Li, Ye, Shen, Le, Weber, Christopher, Khalili-Araghi, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028499/
https://www.ncbi.nlm.nih.gov/pubmed/29915162
http://dx.doi.org/10.1085/jgp.201711868