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Molecular determination of claudin-15 organization and channel selectivity
Tight junctions are macromolecular structures that traverse the space between adjacent cells in epithelia and endothelia. Members of the claudin family are known to determine tight junction permeability in a charge- and size-selective manner. Here, we use molecular dynamics simulations to build and...
Autores principales: | Samanta, Priyanka, Wang, Yitang, Fuladi, Shadi, Zou, Jinjing, Li, Ye, Shen, Le, Weber, Christopher, Khalili-Araghi, Fatemeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028499/ https://www.ncbi.nlm.nih.gov/pubmed/29915162 http://dx.doi.org/10.1085/jgp.201711868 |
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