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Deglycosylation of Shaker K(V) channels affects voltage sensing and the open–closed transition

Most membrane proteins are subject to posttranslational glycosylation, which influences protein function, folding, solubility, stability, and trafficking. This modification has been proposed to protect proteins from proteolysis and modify protein–protein interactions. Voltage-activated ion channels...

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Detalles Bibliográficos
Autores principales: Lopez-Rodriguez, Angelica, Holmgren, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028503/
https://www.ncbi.nlm.nih.gov/pubmed/29880580
http://dx.doi.org/10.1085/jgp.201711958