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A20 and ABIN-1 team up against intestinal epithelial cell death

A20 and its binding partner ABIN-1 are genetically linked to inflammatory diseases. In this issue of JEM, Kattah et al. (https://doi.org/10.1084/jem.20180198) demonstrate that simultaneous deletion in a mouse model leads to instantaneous cell death in the intestinal epithelium and mortality.

Detalles Bibliográficos
Autor principal: Cadwell, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028507/
https://www.ncbi.nlm.nih.gov/pubmed/29934322
http://dx.doi.org/10.1084/jem.20180953