Itraconazole targets cell cycle heterogeneity in colorectal cancer

Cellular dormancy and heterogeneity in cell cycle length provide important explanations for treatment failure after adjuvant therapy with S-phase cytotoxics in colorectal cancer (CRC), yet the molecular control of the dormant versus cycling state remains unknown. We sought to understand the molecula...

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Detalles Bibliográficos
Autores principales: Buczacki, Simon J.A., Popova, Semiramis, Biggs, Emma, Koukorava, Chrysa, Buzzelli, Jon, Vermeulen, Louis, Hazelwood, Lee, Francies, Hayley, Garnett, Mathew J., Winton, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028508/
https://www.ncbi.nlm.nih.gov/pubmed/29853607
http://dx.doi.org/10.1084/jem.20171385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028508/
https://www.ncbi.nlm.nih.gov/pubmed/29853607
http://dx.doi.org/10.1084/jem.20171385

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