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The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination

Type 1 T helper (Th1) cells play a critical role in host defense against intracellular pathogens and in autoimmune diseases by producing a key inflammatory cytokine interferon (IFN)–γ; some Th1 cells can also be antiinflammatory through producing IL-10. However, the molecular switch for regulating t...

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Detalles Bibliográficos
Autores principales: Yu, Fang, Sharma, Suveena, Jankovic, Dragana, Gurram, Rama Krishna, Su, Pan, Hu, Gangqing, Li, Rao, Rieder, Sadiye, Zhao, Keji, Sun, Bing, Zhu, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028509/
https://www.ncbi.nlm.nih.gov/pubmed/29773643
http://dx.doi.org/10.1084/jem.20170155